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Intelligent HVAC gmp clean room For Advanced Materials Research
| Brand Name: | SHP |
| Model Number: | Customized |
| MOQ: | 50 square meters |
| Price: | $500.00/square meters 50-499 square meters |
| Payment Terms: | L/C,T/T |
| Supply Ability: | ≥1 set |
Intelligent HVAC Gmp Clean Room
,Advanced Materials Research Gmp Clean Room
,Clean Room For Advanced Materials Research
High-Precision Climate-Controlled Modular Cleanroom with Intelligent HVAC for Advanced Materials Research
Product Overview
Technical Reference Data
The data below sets out reference configurations for SHP cleanroom systems and associated purification equipment. The actual cleanroom dimensions, airflow rates, filtration setup, pressure differential and environmental-control parameters depend on the required cleanliness classification, the production process and the project design.
Cleanroom System Reference Configuration
| Item | Reference Configuration |
| Cleanroom Type | Modular / Prefabricated Cleanroom |
| Cleanliness Classification | Class 100–100,000 or applicable ISO classification |
| Cleanroom Structure | Modular wall and ceiling panel system |
| Air Purification | HEPA / FFU filtration system |
| HVAC | AHU-based or project-specific HVAC system |
| Air Distribution | FFU ceiling array / ducted air distribution |
| Flooring | Epoxy coating or anti-static PVC flooring |
| Cleanroom Doors | Sealed cleanroom doors |
| Cleanroom Windows | Flush-mounted observation windows |
| Lighting | Cleanroom LED lighting |
| Pressure Control | Positive or negative pressure according to process requirements |
| Environmental Control | Temperature and relative humidity controlled according to project requirements |
| Monitoring | Particle, airflow, pressure and environmental monitoring where required |
FFU Reference Data
| Item | Reference Specification |
| Equipment Type | Fan Filter Unit (FFU) |
| Air Velocity | Approx. 0.45 m/s |
| HEPA Filtration Efficiency | ≥99.995% @ 0.3 μm |
| Power Supply | 220 V / 50 Hz |
| Noise Level | ≤65 dB |
| Housing Options | SS304 / Powder-Coated Steel |
| Speed Control | Speed Controller / Speed Display |
| Installation | Ceiling-mounted or integrated into modular cleanroom ceiling |
HEPA Box Reference Data
| Item | Reference Specification |
| Model | SHPHB-001 |
| HEPA Filter Size | 410 × 410 × 93 mm |
| HEPA Box Size | 455 × 455 × 380 mm |
| Connector Size | 200 × 200 mm |
| Air Volume | 500 m³/h* |
| Installation | Cleanroom ceiling / air supply system |
*Air volume and other operating parameters should be verified against the selected equipment configuration and the project design.
Cleanroom Environmental Control
| Parameter | Engineering Reference |
| Airborne Particles | Controlled according to required ISO classification |
| Airflow | Designed according to room classification and process requirements |
| Differential Pressure | Positive / negative pressure according to process zoning |
| Temperature | Project-specific |
| Relative Humidity | Project-specific |
| Air Changes | Determined by cleanroom classification, heat load and process requirements |
| Filtration | HEPA filtration; additional filtration stages where required |
| Cross-Contamination Control | Airflow zoning, pressure relationships and personnel/material flow design |
Cleanroom Enclosure Materials
| Component | Typical Material / Configuration |
| Wall Panels | Sandwich panel system |
| Ceiling Panels | Sandwich panel system |
| Panel Core | Rock wool or other specified core material |
| Surface Finish | Project-specific cleanroom coating / coated steel surface |
| Doors | Cleanroom sealed door |
| Windows | Double-glazed / flush observation window according to project requirements |
| Floor | Epoxy or anti-static PVC |
| Joints | Sealed cleanroom joints and penetrations |
Supporting Cleanroom Equipment
The cleanroom system can be integrated with supporting equipment according to the project scope:
- Air Shower
- Fan Filter Unit (FFU)
- HEPA Box
- Pass Box
- Clean Bench
- Laminar Air Flow Cabinet
- AHU
- Chiller
- Cleanroom Doors and Windows
- Cleanroom Lighting
Testing & Performance Verification
Following installation and commissioning, applicable cleanroom performance parameters can be tested according to the agreed project requirements.
Typical verification items include:
- Airborne Particle Count
- Airflow Measurement
- Differential Pressure
- Temperature
- Relative Humidity
- HEPA / FFU Performance
- Cleanroom Enclosure Integrity
Where included in the project scope, testing and validation documentation may include commissioning records, cleanroom test reports, DQ, IQ, OQ and PQ documentation.
Engineering Note: The values above are reference data rather than guaranteed parameters for every project. Final equipment selection and cleanroom performance criteria should be verified against the approved engineering design, the applicable standards and project-specific requirements.
Cleanroom Description
| Application | Pharmaceutical | Lab | Electronics |
| Cleanliness | Class 100–100000 or applicable ISO/GMP classification | ISO 5–8 or project-specific classification | ISO 5–8 or project-specific classification |
| Scope |
Structure part; Partition and ceiling panel; door and window,epoxy. |
HVAC part; AHU and chiller; Ducting and piping. |
Electrical part; Lamp,switch and socket; Distribution cabinet. |
| Service | Design and production | Construction and test | Validation and training |
| Wall/ceiling panel | Machine-made or Hand-made sandwich board |
| Clean room equipment | Air shower,FFU,Pass box,Laminar flow cabinet,hepa box |
| Cleanliness | Class 100-100000 |
| Purification system | HVAC, or AC conditioner+FFU |
| Floor | PVC anti-static floor or epoxy-based coating |
| Other addessores | stalinite window,LED panel light,Door,Hand wash sink,storage/shoe cabinet etc |
| Service | Design,manufacturing,construction |
Cleanroom Core Functions
1. Maximized Product Yield
A cleanroom eliminates the invisible variables that silently destroy yield. One stray 0.3μm particle can short a semiconductor die. One colony-forming unit can fail an entire pharmaceutical batch. By stripping airborne particulates, microbes, and chemical contaminants from the production environment through multi-stage filtration, positive pressure cascades, and rigorous personnel protocols, the cleanroom transforms yield from a statistical gamble into a predictable, engineered outcome.
2. Process Stability as a Baseline
A half-degree temperature drift shifts photoresist sensitivity. A ten-percent humidity spike alters powder flow properties. The cleanroom HVAC system locks temperature to ±0.5°C and humidity to ±3% RH around the clock, neutralizing external weather, internal heat loads, and occupancy effects. Every production shift runs under the same environmental conditions — batch after batch, month after month.
3. Measurable Regulatory Compliance
ISO 14644. EU GMP Annex 1. FDA 21 CFR Part 11. These are not suggestions — they are prerequisites for market access. A properly validated cleanroom delivers more than filtered air: it delivers documented proof. Filter integrity certificates. Airflow visualization reports. Recovery time curves. Temperature uniformity maps. When the auditor arrives, you hand over data, not explanations.
4. ESD Protection — Invisible, Indispensable
In high-precision electronics, a single 100-volt electrostatic discharge can punch through a gate oxide layer and destroy a wafer worth tens of thousands of dollars. The cleanroom's conductive flooring, integrated grounding grid, and humidity control form a complete ESD protection network that drains static charges the moment they build. The risk isn't reduced — the path is removed.
5. Physical Cross-Contamination Barrier
Adjacent zones of different cleanliness grades are separated by 5–15 Pa positive pressure differentials — air flows only one way, from clean to less clean. Air showers blast personnel with 25 m/s filtered air. Interlocked pass boxes sanitize incoming materials with UV-C. Every potential contamination pathway — between products, between raw materials and finished goods, between people and processes — is blocked physically, not procedurally.
6. Full-Time, Full-Parameter Traceability
Online particle counters, differential pressure transducers, and temperature/humidity probes stream data continuously to a central BMS/EMS platform. Any parameter excursion triggers an instant alert and an immutable time-stamped record. When a quality event occurs, you don't have to reconstruct what happened — the system has already recorded it. The audit trail is complete, tamper-evident, and regulator-ready.
7. Capital Equipment Protection
A lithography stepper costs tens of millions. A mass spectrometer costs hundreds of thousands. Their accuracy and service life depend directly on environmental cleanliness. The cleanroom is not just a shield for the product — it is a long-term preservation strategy for capital assets, reducing maintenance frequency, extending calibration intervals, and deferring costly component replacements.
8. Total Cost of Ownership Advantage
The upfront investment in a cleanroom is substantial, but the lifecycle economics are decisive. Yield improvement reduces scrap. Regulatory compliance eliminates the cost of production shutdowns, product recalls, and denied market authorizations. Variable-speed fans, heat recovery wheels, and demand-controlled ventilation continuously lower operating energy costs. A well-designed cleanroom typically achieves positive TCO return within three to five years.
9. Cross-Industry Infrastructure Versatility
A cleanroom is not a single-purpose asset. It serves semiconductor lithography today, medical device assembly tomorrow, and lithium battery separator coating the next. The standardized architecture — envelope system, purification HVAC, monitoring platform — is inherently process-agnostic, offering a low-friction path for technology upgrades and production line repurposing as your business evolves.
10. Brand Credibility & Customer Confidence
An in-house, third-party-certified cleanroom is the most tangible proof of manufacturing commitment a company can offer. When prospective clients tour your facility, they see more than a production line — they see a validated controlled environment, complete operating records, and a disciplined operational culture. That dual visual and documentary impact builds a level of trust that no sample or brochure can replicate.
Cleanroom Applications
Pharmaceutical & Biotechnology
Modular cleanroom systems can be configured for pharmaceutical and biotechnology applications requiring controlled airborne contamination, environmental conditions and pressure relationships.
Laboratory & R&D
Prefabricated cleanrooms can be adapted for laboratory, testing and research environments according to the required cleanliness classification and process conditions.
Electronics & Semiconductor
Cleanroom configurations can support electronics and precision manufacturing processes where airborne particle and environmental control are important.
Medical & Healthcare
Cleanroom systems can be configured for selected medical, healthcare and controlled production environments according to applicable project requirements.
Engineering Process
SHP cleanroom projects are carried out through a structured engineering process that runs from initial requirement assessment to installation, commissioning and performance verification. The actual scope and sequence depend on the cleanroom classification, the production process, facility conditions and project requirements.
1. Requirement Assessment
The engineering team reviews the planned application, the required cleanliness classification, room functions, personnel and material flows, production equipment, environmental conditions and available utilities. These requirements serve as the basis for the cleanroom layout and system configuration.
2. Cleanroom Layout & Engineering Design
Based on the confirmed requirements, SHP develops the cleanroom layout and coordinates the enclosure structure, ceiling system, HVAC, air distribution, HEPA/FFU filtration, electrical systems, doors, windows and supporting equipment. Airflow direction, pressure relationships and maintenance access are considered during system design.
3. Equipment & Component Selection
Cleanroom panels, FFUs, HEPA filtration units, AHUs, air showers, pass boxes, cleanroom doors and other components are chosen in line with the approved technical requirements. Equipment specifications are checked for compatibility with the overall cleanroom system.
4. Manufacturing & Quality Inspection
Cleanroom panels and related equipment are manufactured in accordance with the approved specifications. Dimensions, materials, component configuration and other applicable quality-control points are verified before shipment. Manufacturing and inspection records can be provided subject to the project documentation requirements.
5. On-Site Installation
The cleanroom enclosure, HVAC and filtration systems, electrical components and supporting equipment are installed according to the approved layout. Panel joints, ceiling interfaces, doors, windows and service penetrations are sealed and inspected as part of the installation process.
6. Commissioning & System Adjustment
Once installation is complete, the HVAC and purification systems are commissioned. Airflow distribution, pressure relationships and environmental-control settings are adjusted in line with the project design and required operating conditions.
7. Performance Testing & Verification
Applicable cleanroom performance parameters are measured once commissioning is complete. Subject to the project scope, verification can include airborne particle concentration, airflow, differential pressure, temperature, relative humidity and HEPA/FFU performance.
8. Documentation & Project Handover
After testing and system adjustment, SHP provides the agreed project documentation. Depending on the application and contract scope, documentation may include cleanroom drawings, equipment information, commissioning records, test reports, operation manuals and DQ/IQ/OQ/PQ documentation.
The final acceptance criteria are based on the approved engineering design, applicable standards and project-specific requirements.
Project Experience
Mauritius Pharmaceutical Cleanroom Project
Location of Project:
Mauritius
Application Area:
Pharmaceutical Manufacturing
Scope:
Design
HVAC
Installation
Validation
Cleanroom Classification:
ISO 7
Delivery Status:
Successfully Delivered
Cleanroom Testing & Verification
Cleanroom performance should be verified after installation and commissioning in line with the applicable project requirements.
SHP's publicly documented cleanroom projects include on-site inspection and performance verification of installed systems; the Romania turnkey project, for example, involved inspection of wall-panel sealing, doors and windows together with particle-count and airflow measurement of the FFU/HEPA filtration system.
Typical Verification Items
Airborne Particle Count
Airflow Measurement
Differential Pressure
Temperature
Relative Humidity
HEPA/FFU Performance
Cleanroom Enclosure Integrity
Lighting and Other Environmental Parameters Where Required
Validation Documentation
Subject to the project scope, cleanroom documentation can include:
Design Qualification (DQ)
Installation Qualification (IQ)
Operational Qualification (OQ)
Performance Qualification (PQ)
Cleanroom Test Reports
Commissioning Records
Operation and Maintenance Documentation
Testing Evidence
Subject to the availability of project testing documentation, relevant test reports and verification records can be provided as supporting project evidence.
The testing items, acceptance criteria and documentation are defined by the cleanroom classification, the application and the agreed project requirements.
Certifications
SHP operates under a certified quality management system and manufactures cleanroom equipment in line with international standards for quality, safety and performance. The engineering and manufacturing processes are continuously audited to ensure compliance with global cleanroom and HVAC project requirements.
Quality Management System
SHP holds ISO 9001:2015 Quality Management System certification, covering the design, manufacturing and installation of cleanroom systems, sandwich panels and air purification equipment.
Certificate: ISO 9001:2015 Quality Management System Certification
CE Certification for Cleanroom Equipment
In support of international projects and regulatory compliance, major cleanroom equipment supplied by SHP has been assessed for conformity with applicable European directives covering electrical safety and electromagnetic compatibility.
CE-certified equipment includes:
Air Shower Room
Fan Filter Unit (FFU)
Pass Box
CE Certification for Air Shower Room
CE Certification for Fan Filter Unit (FFU)
CE Certification for Pass Box
Commitment to Quality and Compliance
By combining certified manufacturing processes, documented quality-control procedures and project validation services, SHP delivers every cleanroom and HVAC solution in accordance with customer specifications, GMP requirements and international cleanroom standards.
Applicable Standards
ISO 14644 Cleanroom Standards
ISO 9001:2015 Quality Management System
EU Low Voltage Directive (2014/35/EU)
EU Electromagnetic Compatibility Directive (2014/30/EU)
GMP Guidelines for Pharmaceutical Manufacturing
EN1886 Air Handling Unit Standard
Company Profile
Founded in 2003, SHP focuses on cleanroom engineering, manufacturing and purification systems. Drawing on more than 20 years of industry experience, SHP delivers cleanroom design, manufacturing, installation, commissioning and technical support for pharmaceutical, biotechnology, medical, laboratory and electronics applications.
SHP's product range includes modular cleanrooms, cleanroom panels, FFUs, HEPA filter boxes, air showers, pass boxes, AHUs, cleanroom doors and windows and related equipment.
Operating under an ISO 9001:2015 quality management system, SHP supports both individual equipment supply and turnkey cleanroom projects. Its engineering team delivers project-specific solutions according to the required cleanliness classification, process conditions, HVAC requirements and applicable standards.
Related Cleanroom Products
Related Cleanroom Products
- Cleanroom Sandwich Panel
- Fan Filter Unit (FFU)
- HEPA Box
- Air Shower
- Pass Box
- Cleanroom Door
- AHU
